Per- and Polyfluorinated Alkyl Substances (PFAS) are a group of chemical compounds that have become a focal point of attention and concern within the environmental community and the general public due to their emerging contaminant status. These compounds, with diverse industrial applications and commercial product uses, are pervasive in various consumer goods. Among the product categories where PFAS are commonly found are industrial polymers, stain repellents, waterproofing agents, surfactants, packaging materials, and aqueous film-forming foams (AFFF) utilized in firefighting. These compounds are also extremely chemically stable and persistent pollutants in the environment and food.

www.epa.gov/pfas/pfas-explained

Avazyme is one of the first ISO/IEC 17025:2017 laboratories accredited by PJLA, in NC that is specifically accredited for EPA method 1633 (version 4) for 40 PFAS analytes. In addition we offer testing for more than 60 PFAS target analytes in a larger variety of matrices, including food. Avazyme is a member of an AOAC International working group to develop official methods of analysis for PFAS in food. Our combination of PFAS dedicated instruments and expeditious turnaround times, along with experienced, well trained, and proficient personnel allows us to get accurate results quickly to our clients.

Analyte Name Abbreviation CASRN
Perfluorobutanoic acid PFBA 375-22-4
Perfluoropentanoic acid PFPeA 2706-90-3
Perfluorohexanoic acid PFHxA 307-24-4
Perfluoroheptanoic acid PFHpA 375-85-9
Perfluorooctanoic acid PFOA 335-67-1
Perfluorononanoic acid PFNA 375-95-1
Perfluorodecanoic acid PFDA 335-76-2
Perfluoroundecanoic acid PFUnA 2058-94-8
Perfluorododecanoic acid PFDoA 307-55-1
Perfluorotridecanoic acid PFTrDA 72629-94-8
Perfluorotetradecanoic acid PFTeDA 376-06-7
Perfluorobutanesulfonic acid PFBS 375-73-5
Perfluoropentansulfonic acid PFPeS 2706-91-4
Perfluorohexanesulfonic acid PFHxS 355-46-4
Perfluoroheptanesulfonic acid PFHpS 375-92-8
Perfluorooctanesulfonic acid PFOS 1763-23-1
Perfluorononanesulfonic acid PFNS 68259-12-1
Perfluorodecanesulfonic acid PFDS 335-77-3
Perfluorododecanesulfonic acid PFDoS 79780-39-5
1H,1H, 2H, 2H-Perfluorohexane sulfonic acid 4:2 FTS 757124-72-4
1H,1H, 2H, 2H-Perfluorooctane sulfonic acid 6:2 FTS 27619-97-2
1H,1H, 2H, 2H-Perfluorodecane sulfonic acid 8:2 FTS 39108-34-4
1H,1H, 2H, 2H-Perfluorododecane sulfonic acid 10:2 FTS 120226-60-0
Perfluorooctanesulfonamide PFOSA 754-91-6
Heptadecafluoro-N-methyloctanesulphonamide NMeFOSA 31506-32-8
Sulfuramid NEtFOSA 4151-50-2
N-methyl perfluorooctanesulfonamidoacetic acid NMeFOSAA 2355-31-9
N-ethyl perfluorooctanesulfonamidoacetic acid NEtFOSAA 2991-50-6
N-Methylperfluorooctanesulfonamidoethanol NMeFOSE 24448-09-7
N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide NEtFOSE 1691-99-2
Hexafluoropropylene oxide dimer acid HFPO-DA 13252-13-6
4,8-Dioxa-3H-perfluorononanoic acid ADONA 919005-14-4
Perfluoro-3-methoxypropanoic acid PFMPA 377-73-1
Perfluoro-4-methoxybutanoic acid PFMBA 863090-89-5
Nonafluoro-3,6-dioxaheptanoic acid NFDHA 151772-58-6
9-chlorohexadecafluoro-3-oxanone-1-sulfonic acid 9Cl-PF3ONS 756426-58-1d
11-Chloroeicosafluoro-3-oxaundecane-1-sulfonic acid 11Cl-PF3OUdS 763051-92-9
Perfluoro(2-ethoxyethane)sulfonic acid PFEESA 113507-82-7
4,4,5,5,6,6,6-Heptafluorohexanoic acid 3:3 FTCA 356-02-5
2H,2H,3H,3H-Perfluorooctanoic Acid 5:3 FTCA 914637-49-3
2H,2H,3H,3H-Perfluorodecanoic acid 7:3 FTCA 812-70-4

EPA Method 1633

Analyte Name Abbreviation CASRN
Perfluorobutanoic acid PFBA 375-22-4
Perfluoropentanoic acid PFPeA 2706-90-3
Perfluorohexanoic acid PFHxA 307-24-4
Perfluoroheptanoic acid PFHpA 375-85-9
Perfluorooctanoic acid PFOA 335-67-1
Perfluorononanoic acid PFNA 375-95-1
Perfluorodecanoic acid PFDA 335-76-2
Perfluoroundecanoic acid PFUnA 2058-94-8
Perfluorododecanoic acid PFDoA 307-55-1
Perfluorotridecanoic acid PFTrDA 72629-94-8
Perfluorotetradecanoic acid PFTeDA 376-06-7
Perfluorobutanesulfonic acid PFBS 375-73-5
Perfluoropentansulfonic acid PFPeS 2706-91-4
Perfluorohexanesulfonic acid PFHxS 355-46-4
Perfluoroheptanesulfonic acid PFHpS 375-92-8
Perfluorooctanesulfonic acid PFOS 1763-23-1
Perfluorononanesulfonic acid PFNS 68259-12-1
Perfluorodecanesulfonic acid PFDS 335-77-3
Perfluorododecanesulfonic acid PFDoS 79780-39-5
Perfluorooctanesulfonamide FOSA 754-91-6
N-methyl perfluorooctanesulfonamidoacetic acid NMeFOSAA 2355-31-9
N-ethyl perfluorooctanesulfonamidoacetic acid NEtFOSAA 2991-50-6
1H,1H, 2H, 2H-Perfluorohexane sulfonic acid 4:2 FTS 757124-72-4
1H,1H, 2H, 2H-Perfluorooctane sulfonic acid 6:2 FTS 27619-97-2
1H,1H, 2H, 2H-Perfluorodecane sulfonic acid 8:2 FTS 39108-34-4
Sulfuramid NEtFOSA 4151-50-2
Heptadecafluoro-N-methyloctanesulphonamide NMeFOSA 31506-32-8
N-Methylperfluorooctanesulfonamidoethanol NMeFOSE 24448-09-7
N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide NEtFOSE 1691-99-2
Hexafluoropropylene oxide dimer acid HFPO-DA 13252-13-6
11-Chloroeicosafluoro-3-oxaundecane-1-sulfonic acid 11Cl-PF3OUdS 763051-92-9
4,8-Dioxa-3H-perfluorononanoic acid ADONA 919005-14-4
4,4,5,5,6,6,6-Heptafluorohexanoic acid 3:3 FTCA 356-02-5
2H,2H,3H,3H-Perfluorooctanoic Acid 5:3 FTCA 914637-49-3
2H,2H,3H,3H-Perfluorodecanoic acid 7:3 FTCA 812-70-4
Nonafluoro-3,6-dioxaheptanoic acid NFDHA 151772-58-6
Perfluoro-4-methoxybutanoic acid PFMBA 863090-89-5
Perfluoro-3-methoxypropanoic acid PFMPA 377-73-1
Perfluoro(2-ethoxyethane)sulfonic acid PFEESA 113507-82-7

AOAC Method

Analyte Name Abbreviation CASRN
Perfluorobutanoic acid PFBA 375-22-4
Perfluoropentanoic acid PFPeA 2706-90-3
Perfluorohexanoic acid PFHxA 307-24-4
Perfluoroheptanoic acid PFHpA 375-85-9
Perfluorooctanoic acid PFOA 335-67-1
Perfluorononanoic acid PFNA 375-95-1
Perfluorodecanoic acid PFDA 335-76-2
Perfluoroundecanoic acid PFUnA 2058-94-8
Perfluorododecanoic acid PFDoA 307-55-1
Perfluorotridecanoic acid PFTrDA 72629-94-8
Perfluorotetradecanoic acid PFTeDA 376-06-7
Perfluorobutanesulfonic acid PFBS 375-73-5
Perfluoropentansulfonic acid PFPeS 2706-91-4
Perfluorohexanesulfonic acid PFHxS 355-46-4
Perfluoroheptanesulfonic acid PFHpS 375-92-8
Perfluorooctanesulfonic acid PFOS 1763-23-1
Perfluorononanesulfonic acid PFNS 68259-12-1
Perfluorodecanesulfonic acid PFDS 335-77-3
Perfluoroundecanesulfonic acid PFUnDS PFUnDS
Perfluorododecanesulfonic acid PFDoS 79780-39-5
Perfluorotridecanesulfonic acid PFTrDS 791563-89-8
Perfluorooctanesulfonamide PFOSA 754-91-6
9-Chlorohexadecafluoro-3-oxanonane-1-sulfonic acid 9Cl-PF3ONS 756426-58-1
11-Chloroeicosafluoro-3-oxaundecane-1-sulfonic acid 11Cl-PF3OUdS 763051-92-9
Hexafluoropropylene oxide dimer acid HFPO-DA 13252-13-6
4,8-Dioxa-3H-perfluorononanoic acid DONA 919005-14-4
1H,1H, 2H, 2H-Perfluorohexane sulfonic acid 4:2 FTS 757124-72-4
1H,1H, 2H, 2H-Perfluorooctane sulfonic acid 6:2 FTS 27619-97-2
1H,1H, 2H, 2H-Perfluorodecane sulfonic acid 8:2 FTS 39108-34-4
1H,1H, 2H, 2H-Perfluorododecane sulfonic acid 10:2 FTS 120226-60-0
6:2 Fluorotelomer phosphate monoester 6:2PAP 57678-01-0
8:2 Fluorotelomer phosphate monoester 8:2PAP 57678-03-2
6:2 Fluorotelomer phosphate dieste 6:2diPAP 57677-95-9
8:2 Fluorotelomer phosphate diester 8:2diPAP 114519-85-6
Capstone A 80475-32-7
Capstone B 34455-29-3
2-Perfluorobutyl ethanol (4:2) 4:2 FTOH 2043-47-2
2-Perfluorohexyl ethanol (6:2) 6:2 FTOH 647-42-7
2-Perfluorooctyl ethanol (8:2) 8:2 FTOH 678-39-7
2-Perfluorodecyl ethanol (10:2) 10:2 FTOH 865-86-1

533 Method

Analyte Name Abbreviation CASRN
11-Chloroeicosafluoro-3-oxaundecane-1-sulfonic acid 11Cl-PF3OUdS 763051-92-9
9-Chlorohexadecafluoro-3-oxanonane-1-sulfonic acid 9Cl-PF3ONS 756426-58-1
4,8-Dioxa-3H-perfluorononanoic acid ADONA 919005-14-4
Hexafluoropropylene oxide dimer acid HFPO-DA 13252-13-6
Nonafluoro-3,6-dioxaheptanoic acid NFDHA 151772-58-6
Perfluorobutanoic acid PFBA 375-22-4
Perfluorobutanesulfonic acid PFBS 375-73-5
1H,1H, 2H, 2H-Perfluorodecane sulfonic acid 8:2FTS 39108-34-4
Perfluorodecanoic acid PFDA 335-76-2
Perfluorododecanoic acid PFDoA 307-55-1
Perfluoro(2-ethoxyethane)sulfonic acid PFEESA 113507-82-7
Perfluoroheptanesulfonic acid PFHpS 375-92-8
Perfluoroheptanoic acid PFHpA 375-85-9
1H,1H, 2H, 2H-Perfluorohexane sulfonic acid 4:2FTS 757124-72-4
Perfluorohexanesulfonic acid PFHxS 355-46-4
Perfluoroheptanoic acid PFHpA 375-85-9
1H,1H, 2H, 2H-Perfluorohexane sulfonic acid 4:2FTS 757124-72-4
Perfluorohexanesulfonic acid PFHxS 355-46-4
Perfluorohexanoic acid PFHxA 307-24-4
Perfluoro-3-methoxypropanoic acid PFMPA 377-73-1
Perfluoro-4-methoxybutanoic acid PFMBA 863090-89-5
Perfluorononanoic acid PFNA 375-95-1
1H,1H, 2H, 2H-Perfluorooctane sulfonic acid 6:2FTS 27619-97-2
Perfluorooctanesulfonic acid PFOS 1763-23-1
Perfluorooctanoic acid PFOA 335-67-1
Perfluoropentanoic acid PFPeA 2706-90-3
Perfluoropentanesulfonic acid PFPeS 2706-91-4
Perfluoroundecanoic acid PFUnA 2058-94-8

537.1 Method

Analyte Name Abbreviation CASRN
Hexafluoropropylene oxide dimer acid HFPO-DA 13252-13-6b
N-ethyl perfluorooctanesulfonamidoacetic acid NEtFOSAA 2991-50-6
N-methyl perfluorooctanesulfonamidoacetic acid NMeFOSAA 2355-31-9
Perfluorobutanesulfonic acid PFBS 375-73-5
Perfluorodecanoic acid PFDA 335-76-2
Perfluorododecanoic acid PFDoA 307-55-1
Perfluoroheptanoic acid PFHpA 375-85-9
Perfluorohexanesulfonic acid PFHxS 355-46-4
Perfluorohexanoic acid PFHxA 307-24-4
Perfluorononanoic acid PFNA 375-95-1
Perfluorooctanesulfonic acid PFOS 1763-23-1
Perfluorooctanoic acid PFOA 335-67-1
Perfluorotetradecanoic acid PFTA 376-06-7
Perfluorotridecanoic acid PFTrDA 72629-94-8
Perfluoroundecanoic acid PFUnA 2058-94-8
11-chloroeicosafluoro-3-oxaundecane-1-sulfonic acid 11Cl-PF3OUdS 763051-92-9c
9-chlorohexadecafluoro-3-oxanone-1-sulfonic acid 9Cl-PF3ONS 756426-58-1d
4,8-dioxa-3H-perfluorononanoic acid ADONA 919005-14-4e

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